Ehlers-Danlos Syndrome: a genetic defect in collagen (a protein that acts as the body’s “glue” -adding strength and elasticity to connective tissue.) Collagen provides support to many body parts such as the skin, muscles, ligaments, and blood vessels. As a result of of faulty or reduced amounts of collagen, patients with EDS may have stretchy, fragile skin, fragile blood vessels prone to ruptures, and unstable joints.
Craniocervical Instability (CCI): a structural instability of the craniocervical junction which may lead to a pathological deformation of the brainstem, upper spinal cord, and cerebellum. It primarily occurs in patients with Ehlers-Danlos Syndrome and other hereditary disorders of connective tissue.